N. Muge Kuyumcu-Martinez, Ph.D., Assistant Professor
Our laboratory’s main focus is to understand the regulation of post-transcriptional networks in normal and diseased heart. We are specifically interested in how protein kinase C signaling influences post-transcriptional changes and how these changes may contribute to the pathogenesis of diabetic cardiomyopathy.
In our laboratory, we would like to address these questions using mouse and cell culture models:
- How do post-transcriptional networks change in diabetic hearts?
- Which RNA binding proteins are involved in the regulation of these networks?
- How do these post-transcriptional events respond to protein kinase C (PKC) signaling pathway, which is involved in the pathogenesis of diabetes?
- How do changes in post-transcriptional networks affect heart metabolism and function?
The findings from our studies will provide new ways to prevent or cure cardiac problems in diabetes patients.
Current Lab Members
Vaibhav DeshmukhSunil Verma, PhD
