Our research is carried out in the Department of Biochemistry and Molecular Biology at UTMB. The laboratory is co-directed by Drs. Bradrick and Garcia-Blanco and is focused on two areas of biomedical importance: (i) host-pathogen interactions involving pathogenic flaviviruses such as dengue, yellow fever and zika viruses, and (ii) alternative splicing regulation of the interleukin-7 receptor alpha (IL7Rα) pre-mRNA and its connection to autoimmunity, especially in the context of multiple sclerosis.