International Workshop

Protein-DNA Interactions: from Biophysics to Cancer Biology

December 7-8, 2017
Houston, Texas

Program

DAY1: Thursday, December 7

 

8:00am:                    Registration and Breakfast, BRC 1-st floor lobby

 

8:55am:                     Introduction:  Anatoly Kolomeisky (Rice University) BRC auditorium;

 

Session 1 (BRC Auditorium)        Chair:  Anatoly Kolomeisky (Rice University)

 

9:00am-9:30am:      Yaakov (Koby) Levy (Weizmann Institute of Science, Israel),

MOLECULAR PRINCIPLES FOR OPTIMIZING PROTEIN-DNA INTERACTIONS

 

9:30am-10:00am:    Ido Golding (Baylor College of Medicine),

DECIPHERING THE STOCHASTIC KINETICS OF GENE REGULATION

 

10:00am-10:30am:  Courtney Hodges (Baylor College of Medicine)

SWI/SNF IN CANCER: HOW A BROKEN ATPase ALTERS THE OPEN CHROMATIN LANDSCAPE

 

10:30am-11:00am: Coffee Break (BRC 1-st floor lobby)

 

11:00am-11:30am:  Charles Schroeder (University of Illinois at Urbana–Champaign),

                                DIRECT OBSERVATION OF TALE PROTEIN DYNAMICS ON DNA

 

11:30am-noon:        Peter Wolynes (Rice University),

                                    TBD

 

Noon-2:00pm:          Lunch (BRC 1-st floor lobby)

& Poster Session (BRC expositions area – 1-st floor)

 

Session 2 (BRC Auditorium)        Chair:  Junji Iwahara (University of Texas Medical Branch)

 

2:00pm-2:30pm:      Xiadong Cheng (MD Anderson Cancer Center, University of Texas)

GENERATION, RECOGNITION, AND ERASURE (GRE) of 5-METHYLCYTOSINE AND ITS OXIDATIVE DERIVATIVES        

 

2:30pm-3:00pm:      James Stivers (Johns Hopkins University),

TRACKING ENZYME MOVEMENT ON DNA: FROM TEST TUBE TO CELL

 

3:00pm-3:30pm:      Andrew Spakowitz (Stanford University),

PHYSICA MODELING OF CHROMOSOMAL ORGANIZATION AND EPIGENETIC REGULATION

 

3:30pm-4:00pm:      Cofee Break (BRC 1-st floor lobby)

 

4:00pm-4:30pm:      Tatiana Kutateladze (University of Colorado Denver)

                                 MOLECULAR MECHANISMS OF THE EPIGENETIC REGULATION

 

4:30pm-5:00pm:      Erez Lieberman Aiden (Baylor College of Medicine),

                                    TBD

 

6:00pm:                     Dinner for Invited Speakers and organizers

 

 

DAYS 2: Friday, December 8

 

8:00am:                    Breakfast, BRC 1-st floor lobby;

 

Session 3 (BRC Auditorium)        Chair: Chin-Yo Lin (University of Houston)

 

9:00am-9:30am:      Montgomery Pettitt (University of Texas Medical Branch)

DNA SHAPE VERSUS SEQUENCE VARIATIONS IN PROTEIN BINDING

 

9:30am-10:00am:    Gordon Hager (National Institute of Cancer),

TRANSCRIPTION FACTOR ACTION IN THE NUCLEUS: INTEGRATING GENOME WIDE AND REAL TIME DYNAMIC DATASETS

 

10:00am-10:30am:  Yijun Ruan (Jackson Laboratory),

3D GENOME ORGANIZATION & TRANSCRIPTION REGULATION IN CANCER CELLS

 

 

10:30am-11:00am: Coffee Break (BRC 1-st floor lobby)

 

11:00am-11:30am:  Jose Onuchic (Rice University)

EXPLORING PROTEIN FUNCTION: THE CONVERGENCE OF STRUCTURE BASED MODELS AND CO-EVOLUTIONARY INFORMATION

 

11:30am-noon:        Yael Mandel-Gutfreund (Technion, Israel)

A ROLE OF THE MOTIF ENVIRONMENT ON TRANSCRIPTION FACTOR BINDING

 

Noon-2:00pm:          Lunch (BRC 1-st floor lobby)

& Poster Session (BRC expositions area – 1-st floor)

 

Session 4 (BRC Auditorium)        Chair:  Peng Guang (MD Anderson Cancer Center)

 

2:00pm-2:30pm:      Alexei Kornyshev (Imperial College London, UK),

DNA CAN RECOGNIZE SEQUENCE HOMOLOGY WITHOUT PROTEINS – THEORY AND NEW EXPERIMENTAL EVIDENCES

 

2:30pm-3:00pm:      Tamas Fischer (Australian National University)

NUCLEOSOME DYNAMICS, PERVASIVE TRANSCRIPTION AND GENOME STABILITY

 

3:00pm-3:30pm:      Binghui Shen (Beckman Research Institute/ City of Hope)

DNA STRUCTURE-SPECIFIC ACTION OF NUCLEASES IN MINIMIZING MUTATION AND CANCER INCIDENCE

 

3:30pm-4:00pm:      Coffee Break (BRC 1-st floor lobby)

 

4:00pm-4:30pm:      Ilya Finkelstein (University of Texas Austin)

HACKING NGS TO REVEAL THE MOLECULAR BASIS FOR THE DNA-BINDING SPECIFICITY OF Cpf1 AND Cas9

 

4:30PM-5:00pm:      Margaret Cheung (University of Houston),

MOLECULAR UNDERPINNING OF POSTSYNAPTIC CALMODULIN-DEPENDENT CALCIUM SIGNALING

                       

6:00pm:                     Dinner for Invited Speakers and organizers                                   

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